| Primary Identifier | MGI:98431 | Organism | mouse, laboratory |
| Chromosome | 5 | NCBI Gene Number | 20860 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables steroid sulfotransferase activity. Involved in estrogen metabolic process. Acts upstream of or within female pregnancy. Located in cytoplasm. Is expressed in liver; nervous system; nose; and reproductive system. Human ortholog(s) of this gene implicated in breast cancer and endometrial cancer. Orthologous to human SULT1E1 (sulfotransferase family 1E member 1). PHENOTYPE: Homozygous null mice exhibit reduced fertility. Males exhibit abnormal testis morphology with Leydig cell hypertrophy and hyperplasia and reduced caudal sperm motility. Spontaneous fetal loss caused by placental thrombosis occurs in pregnant females. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
