Primary Identifier | MGI:104655 | Organism | mouse, laboratory |
Chromosome | 5 | NCBI Gene Number | 11698 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables growth factor activity. Involved in cell adhesion and regulation of cell population proliferation. Predicted to be located in extracellular matrix. Is expressed in several structures, including jaw. Human ortholog(s) of this gene implicated in amelogenesis imperfecta type 1F. Orthologous to human AMBN (ameloblastin). PHENOTYPE: Homozygous null mice lack enamel and display abnormal ameloblast and tooth morphology and an increased incidence of dental epithelium derived tumors. [provided by MGI curators] |