| Primary Identifier | MGI:106484 | Organism | mouse, laboratory |
| Chromosome | 5 | NCBI Gene Number | 52822 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Involved in several processes, including positive regulation of axon extension; positive regulation of intracellular protein transport; and regulation of establishment of cell polarity. Acts upstream of or within positive regulation of axonogenesis. Located in growth cone and perikaryon. Is expressed in several structures, including alimentary system; eye; genitourinary system; hemolymphoid system; and nervous system. Orthologous to human RUFY3 (RUN and FYVE domain containing 3). PHENOTYPE: The gene product is involved in regulating neuronal polarity and axon growth. Homozygous KO leads to loss of neuronal polarity and causes neonatal lethality. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
