Primary Identifier | MGI:102726 | Organism | mouse, laboratory |
Chromosome | 5 | NCBI Gene Number | 13178 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables deoxyadenosine kinase activity. Involved in dAMP salvage. Predicted to be located in nucleoplasm. Predicted to be active in mitochondrion. Is expressed in several structures, including alimentary system; integumental system; midbrain; nose; and telencephalon. Orthologous to human DCK (deoxycytidine kinase). PHENOTYPE: Mice homozygous for disruptions in this gene have profound defects in lymphopoiesis. Thymic T cell number and overall lymphocyte number are greatly reduced. [provided by MGI curators] |