Primary Identifier | MGI:1339941 | Organism | mouse, laboratory |
Chromosome | 5 | NCBI Gene Number | 20309 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables chemokine activity. Acts upstream of or within hemopoiesis; inflammatory response; and neutrophil chemotaxis. Located in extracellular region. Is expressed in several structures, including arterial system; central nervous system; embryo mesenchyme; umbilical vein; and yolk sac. PHENOTYPE: Mice homozygous for a targeted null mutation are viable and fertile but display reduced host defense against the pulmonary pathogen Klebsiella pneumoniae. [provided by MGI curators] |