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Protein Coding Gene : Cxcl1 C-X-C motif chemokine ligand 1

Primary Identifier  MGI:108068 Organism  mouse, laboratory
Chromosome  5 NCBI Gene Number  14825
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to enable chemokine activity. Involved in several processes, including positive regulation of hematopoietic stem cell proliferation; positive regulation of neutrophil mediated killing of fungus; and positive regulation of superoxide anion generation. Located in extracellular space. Is expressed in several structures, including cardiovascular system; liver; nervous system; retina; and small intestine. Orthologous to human CXCL1 (C-X-C motif chemokine ligand 1) and CXCL2 (C-X-C motif chemokine ligand 2).
PHENOTYPE: Targeted mutations in this gene when combine with targeted mutation of Ldlr decreases susceptibility to atherosclerotic lesions. [provided by MGI curators]
  • synonyms:
  • MGD-MRK-12226,
  • KC,
  • Scyb1,
  • fibroblast secretory protein,
  • Cxcl1,
  • Fsp,
  • GRO1 oncogene,
  • Gro1,
  • N51,
  • melanoma growth stimulatory activity,
  • MGD-MRK-9878,
  • MGD-MRK-37105,
  • KC/GRO-alpha,
  • C-X-C motif chemokine ligand 1,
  • Mgsa

Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

4 Involved In Mutations

0 Strain

0 Transcripts

1 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

11 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

1 Driver For