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Protein Coding Gene : Epgn epithelial mitogen

Primary Identifier  MGI:1919170 Organism  mouse, laboratory
Chromosome  5 NCBI Gene Number  71920
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Enables growth factor activity and transmembrane receptor protein tyrosine kinase activator activity. Involved in epidermal growth factor receptor signaling pathway and positive regulation of epithelial cell proliferation. Acts upstream of or within MAPK cascade. Is active in extracellular space. Is expressed in several structures, including alimentary system; arterial system; dorsal root ganglion; hair follicle; and male reproductive gland or organ. Orthologous to human EPGN (epithelial mitogen).
PHENOTYPE: Mice homozygous for a knock-out allele exhibit moderate increase in absolute pancreas and spleen weight but normal epidermis and pilosebaceous unit development. [provided by MGI curators]
  • synonyms:
  • epigen,
  • epithelial mitogen,
  • 2310069M11Rik,
  • RIKEN cDNA 2310069M11 gene,
  • Epgn

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

4 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

22 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For