| Primary Identifier | MGI:99439 | Organism | mouse, laboratory |
| Chromosome | 5 | NCBI Gene Number | 12223 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables receptor ligand activity and transmembrane receptor protein tyrosine kinase activator activity. Involved in ERBB2-EGFR signaling pathway. Acts upstream of or within negative regulation of epithelial cell apoptotic process and positive regulation of cell population proliferation. Is active in extracellular space. Is expressed in heart; lung; pancreas; reproductive system; and skin. Human ortholog(s) of this gene implicated in type 1 diabetes mellitus and type 2 diabetes mellitus. Orthologous to human BTC (betacellulin). PHENOTYPE: Mice homozygous for a knock-out allele are viable and fertile and exhibit no overt defects. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
