Primary Identifier | MGI:1915348 | Organism | mouse, laboratory |
Chromosome | 5 | NCBI Gene Number | 68098 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable several functions, including p53 binding activity; protein homodimerization activity; and zinc ion binding activity. Predicted to be involved in several processes, including positive regulation of protein metabolic process; protein autoubiquitination; and rescue of stalled ribosome. Predicted to be located in cytosol and nucleoplasm. Predicted to be part of ubiquitin ligase complex. Predicted to be active in nucleus. Orthologous to human RCHY1 (ring finger and CHY zinc finger domain containing 1). PHENOTYPE: Mouse embryonic fibroblasts from mice homozygous for a knock-out allele exhibit decreased cellular sensitivity to UV irradiation. [provided by MGI curators] |