| Primary Identifier | MGI:107569 | Organism | mouse, laboratory |
| Chromosome | 11 | NCBI Gene Number | 13861 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 9.1.0) Enables peroxidase activity. Involved in antibacterial innate immune response. Acts upstream of or within defense response to nematode; eosinophil migration; and regulation of cytokine production. Predicted to be active in extracellular region. Is expressed in bone marrow. Orthologous to human EPX (eosinophil peroxidase). PHENOTYPE: Targeted deletion of this gene results in ultrastructural changes of the eosinophil secondary granule but does not significantly alter the course of inflammation or development of allergic pulmonary pathologies in an ovalbumin-challenge model of pulmonary inflammation. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
