Primary Identifier | MGI:2443154 | Organism | mouse, laboratory |
Chromosome | 5 | NCBI Gene Number | 231464 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables poly(A)-specific ribonuclease activity. Acts upstream of or within nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay and positive regulation of cell population proliferation. Located in cytoplasm. Is expressed in several structures, including brain; genitourinary system; gut; hemolymphoid system gland; and musculature. Orthologous to human CNOT6L (CCR4-NOT transcription complex subunit 6 like). PHENOTYPE: Mice homozygous for a knock-out allele exhibit protection from diet-induced obesity and metabolic disruptions. [provided by MGI curators] |