Primary Identifier | MGI:88179 | Organism | mouse, laboratory |
Chromosome | 5 | NCBI Gene Number | 110075 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable BMP receptor binding activity; cytokine activity; and growth factor activity. Acts upstream of or within positive regulation of transcription by RNA polymerase II. Predicted to be located in vesicle. Predicted to be active in extracellular space. Is expressed in several structures, including alimentary system; brain; embryo mesenchyme; skeleton; and urinary system. Orthologous to human BMP3 (bone morphogenetic protein 3). PHENOTYPE: Homozygous mutation of this gene results in increased bone density. [provided by MGI curators] |