| Primary Identifier | MGI:2176740 | Organism | mouse, laboratory |
| Chromosome | 5 | NCBI Gene Number | 191578 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable single-stranded 3'-5' DNA helicase activity. Involved in positive regulation of double-strand break repair via homologous recombination. Predicted to be part of single-stranded DNA-dependent ATP-dependent DNA helicase complex. Predicted to be active in nucleus and site of DNA damage. Orthologous to human HELQ (helicase, POLQ like). PHENOTYPE: Mice homozygous for a knock-out allele exhibit reduced fertility and increased incident of tumors. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
