| Primary Identifier | MGI:1917931 | Organism | mouse, laboratory |
| Chromosome | 5 | NCBI Gene Number | 70681 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable microtubule binding activity and polyubiquitin modification-dependent protein binding activity. Predicted to be involved in several processes, including mitotic G2 DNA damage checkpoint signaling; nuclear chromosome segregation; and positive regulation of DNA repair. Predicted to be located in nuclear body. Predicted to be part of BRCA1-A complex. Predicted to be active in nucleus. Orthologous to human ABRAXAS1 (abraxas 1, BRCA1 A complex subunit). PHENOTYPE: Mice homozygous for a knock-out allele exhibit increased tumor incidence, genetic instability and premature lethality. Mice heterozygous for a knock-out allele exhibit increased tumor incidence and premature death. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
