| Primary Identifier | MGI:1346863 | Organism | mouse, laboratory |
| Chromosome | 5 | NCBI Gene Number | 26414 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables JUN kinase activity. Involved in several processes, including JNK cascade; locomotor rhythm; and protein phosphorylation. Located in mitochondrion; plasma membrane; and postsynaptic density. Is expressed in several structures, including genitourinary system; gut; heart; nervous system; and sensory organ. Human ortholog(s) of this gene implicated in pancreatic adenocarcinoma. Orthologous to human MAPK10 (mitogen-activated protein kinase 10). PHENOTYPE: Mice homozygous for disruptions in this gene display a normal phenotype. They are resistant to kainic acid induced seizures and show increased resistance to MPTP induced Parkinson's disease. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
