| Primary Identifier | MGI:103293 | Organism | mouse, laboratory |
| Chromosome | 5 | NCBI Gene Number | 19249 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable phosphatidylinositol 3-kinase regulatory subunit binding activity and protein tyrosine phosphatase activity. Predicted to be involved in several processes, including negative regulation of excitatory synapse assembly; peptidyl-tyrosine dephosphorylation; and regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction. Located in cytoplasm; midbody; and nucleus. Is expressed in several structures, including brain; epithelium; genitourinary system; gut; and humerus cartilage condensation. Human ortholog(s) of this gene implicated in breast cancer; carcinoma (multiple); and colorectal cancer (multiple). Orthologous to human PTPN13 (protein tyrosine phosphatase non-receptor type 13). PHENOTYPE: Mice homozygous for a null allele exhibit abnormal T-helper cell differentiation. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
