Primary Identifier | MGI:2141353 | Organism | mouse, laboratory |
Chromosome | 5 | NCBI Gene Number | 433926 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable volume-sensitive anion channel activity. Predicted to be involved in several processes, including aspartate transmembrane transport; cyclic-GMP-AMP transmembrane import across plasma membrane; and monoatomic anion transmembrane transport. Predicted to be located in endoplasmic reticulum membrane. Predicted to be part of monoatomic ion channel complex. Predicted to be active in cytoplasm and plasma membrane. Orthologous to human LRRC8B (leucine rich repeat containing 8 VRAC subunit B). PHENOTYPE: Mice homozygous for a null allele exhibit normal response to viral infection. [provided by MGI curators] |