| Primary Identifier | MGI:1891374 | Organism | mouse, laboratory |
| Chromosome | 5 | NCBI Gene Number | 114642 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables histone reader activity and lysine-acetylated histone binding activity. Involved in several processes, including male meiosis I; regulation of RNA splicing; and sperm DNA condensation. Acts upstream of or within with a positive effect on positive regulation of gene expression. Located in nucleus. Is expressed in several structures, including 1st branchial arch maxillary component; central nervous system; genitourinary system; limb; and maxillary process. Human ortholog(s) of this gene implicated in azoospermia; oligospermia; and spermatogenic failure 21. Orthologous to human BRDT (bromodomain testis associated). PHENOTYPE: Homozygous inactivation of this genes leads to arrest of spermatogenesis and male infertility. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
