| Primary Identifier | MGI:1919642 | Organism | mouse, laboratory |
| Chromosome | 5 | NCBI Gene Number | 72392 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables potassium ion leak channel activity. Involved in lysosome organization; neuron cellular homeostasis; and potassium ion transmembrane transport. Predicted to be located in endosome membrane and lysosomal membrane. Predicted to be active in endosome and lysosome. Orthologous to human TMEM175 (transmembrane protein 175). PHENOTYPE: Mice homozygous and heterozygous for a null allele exhibit dopaminergic neuron loss and impaired lysosomal K+ current in neurons. Heterozygotes also show impaired coordination. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
