Primary Identifier | MGI:1276124 | Organism | mouse, laboratory |
Chromosome | 5 | NCBI Gene Number | 75560 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable chromatin binding activity and protein antigen binding activity. Predicted to be involved in DNA repair; positive regulation of double-strand break repair via homologous recombination; and regulation of cell cycle. Located in nuclear speck. Is expressed in several structures, including adrenal gland; central nervous system; genitourinary system; gut; and trachea. Orthologous to human EP400 (E1A binding protein p400). PHENOTYPE: Mice homozygous for a knock-out allele die at E11.5 and display severe defects in yolk sac erythropoiesis, anemia, and a slight deformity of the neural tube. [provided by MGI curators] |