| Primary Identifier | MGI:2385228 | Organism | mouse, laboratory |
| Chromosome | 5 | NCBI Gene Number | 231633 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Involved in several processes, including endochondral ossification; negative regulation of bone resorption; and positive regulation of macromolecule metabolic process. Acts upstream of or within osteoblast differentiation. Located in endoplasmic reticulum and plasma membrane. Is expressed in several structures, including alimentary system; brain; genitourinary system; limb; and skeleton. Orthologous to human TMEM119 (transmembrane protein 119). PHENOTYPE: Mice homozygous for a targeted allele exhibit growth retardation associated with delayed endochondral bone ossification and impaired osteoblast differentiation. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
