Primary Identifier | MGI:1345964 | Organism | mouse, laboratory |
Chromosome | 5 | NCBI Gene Number | 23790 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables small GTPase binding activity. Involved in several processes, including activation of GTPase activity; regulation of fibroblast migration; and regulation of ruffle assembly. Acts upstream of or within corpus callosum development and ventricular system development. Located in cytoskeleton. Part of flotillin complex. Is expressed in several structures, including brain; dorsal root ganglion; genitourinary system; liver; and spleen. Orthologous to human CORO1C (coronin 1C). PHENOTYPE: Mice exhibit reduced hearing sensitivity, reduced acoustic startle response, hypoactivity, and less frequent urination. [provided by MGI curators] |