| Primary Identifier | MGI:94859 | Organism | mouse, laboratory |
| Chromosome | 5 | NCBI Gene Number | 13142 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables D-amino-acid dehydrogenase activity; D-amino-acid oxidase activity; and FAD binding activity. Involved in several processes, including D-alanine catabolic process; dopamine biosynthetic process; and neutrophil-mediated killing of gram-negative bacterium. Acts upstream of or within L-leucine metabolic process. Located in extracellular space and peroxisomal matrix. Is expressed in metanephros; renal cortex; ureter; and urinary system. Human ortholog(s) of this gene implicated in schizophrenia. Orthologous to human DAO (D-amino acid oxidase). PHENOTYPE: Homozygous null mice display increased levels of D-serine and a decrease in the severity of behavioral effects induced by NMDA receptor antagonists. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
