| Primary Identifier | MGI:1861457 | Organism | mouse, laboratory |
| Chromosome | 5 | NCBI Gene Number | 56455 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables dynein intermediate chain binding activity and protein domain specific binding activity. Acts upstream of or within several processes, including cilium organization; mitocytosis; and positive regulation of non-motile cilium assembly. Located in cytoskeleton; cytosol; and membrane. Part of cytoplasmic dynein complex. Is expressed in several structures, including central nervous system; liver; lung; node; and sensory organ. Orthologous to human DYNLL1 (dynein light chain LC8-type 1). PHENOTYPE: Mice carrying a knock-out mutation of this gene exhibit preweaning lethality. Mice homozygous for a gene trap allele exhibit heterotaxia, small or absent lungs and abnormal cilia. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
