Primary Identifier | MGI:1344408 | Organism | mouse, laboratory |
Chromosome | 5 | NCBI Gene Number | 23980 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable ATP binding activity; mitogen-activated protein kinase binding activity; and receptor serine/threonine kinase binding activity. Acts upstream of or within sperm capacitation. Located in cell surface. Is expressed in cerebral cortex ventricular layer; cortical plate; embryo; ovary; and primary sex cord. Human ortholog(s) of this gene implicated in prostate cancer. Orthologous to human PEBP1 (phosphatidylethanolamine binding protein 1). PHENOTYPE: Mice homozygous for a null allele exhibit age-related decrease in olfactory function. Conditional KO in neurons affects cholinergic neuronal axon projections to the hippocampus. [provided by MGI curators] |