| Primary Identifier | MGI:1924223 | Organism | mouse, laboratory |
| Chromosome | 5 | NCBI Gene Number | 231670 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable DNA binding activity. Acts upstream of or within several processes, including ERK1 and ERK2 cascade; hematopoietic stem cell differentiation; and hematopoietic stem cell homeostasis. Is expressed in nervous system and neural retina. Orthologous to human FBXO21 (F-box protein 21). PHENOTYPE: Mice homozygous for a conditional allele activated in hematopoietic cells exhibit increased susceptibility to 5-FU-induced bone marrow failure and lethality. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
