| Primary Identifier | MGI:1352744 | Organism | mouse, laboratory |
| Chromosome | 5 | NCBI Gene Number | 14357 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable Notch binding activity; ubiquitin protein ligase activity; and ubiquitin protein ligase binding activity. Acts upstream of or within several processes, including Notch signaling pathway; cellular response to leukemia inhibitory factor; and negative regulation of T cell differentiation. Predicted to be located in cytosol and nuclear body. Predicted to be active in nucleoplasm. Is expressed in several structures, including alimentary system; cardiovascular system; central nervous system; genitourinary system; and sensory organ. Orthologous to human DTX1 (deltex E3 ubiquitin ligase 1). PHENOTYPE: Homozygous mutant mice are viable and fertile with normal B and T cell devlepment and function and no gross abnormalities in any of the major organs. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
