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Protein Coding Gene : Adam1b a disintegrin and metallopeptidase domain 1b
Primary Identifier  MGI:2429506 Organism  mouse, laboratory
Chromosome  5 NCBI Gene Number  280667
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to enable metalloendopeptidase activity. Predicted to be involved in binding activity of sperm to zona pellucida; male gonad development; and proteolysis. Predicted to be located in membrane. Predicted to be active in external side of plasma membrane and sperm head plasma membrane. Orthologous to human ADAM1B (ADAM metallopeptidase domain 1B (pseudogene)).
PHENOTYPE: Mice homozygous for a knock-out allele are viable, healthy and fertile with no significant defects in sperm function. [provided by MGI curators]
  • synonyms:
  • expressed sequence AW050088,
  • fertilin alpha,
  • a disintegrin and metalloproteinase domain 1a (fertilin alpha),
  • Ftna,
  • a disintegrin and metallopeptidase domain 1b,
  • AW050088,
  • Adam1,
  • PH-30 alpha,
  • Adam1b
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Features --> Cross References

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2 Involved In Mutations

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Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

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