| Primary Identifier | MGI:1919649 | Organism | mouse, laboratory |
| Chromosome | 5 | NCBI Gene Number | 72399 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable identical protein binding activity; nuclear localization sequence binding activity; and ubiquitin protein ligase activity. Predicted to be involved in Ras protein signal transduction; negative regulation of signal transduction; and protein ubiquitination. Predicted to act upstream of or within MAPK cascade. Predicted to be located in cytosol; nuclear membrane; and nucleoplasm. Predicted to be part of ubiquitin ligase complex. Predicted to be active in cytoplasm. Is expressed in several structures, including central nervous system; dorsal root ganglion; genitourinary system; retina; and vibrissa. Orthologous to human BRAP (BRCA1 associated protein). PHENOTYPE: Mice homozygous for a knock-out allele exhibit embryonic lethality during organogenesis and subtle defects in cell cycle-dependent nuclear movement in neural progenitors. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
