Primary Identifier | MGI:104872 | Organism | mouse, laboratory |
Chromosome | 5 | NCBI Gene Number | 19047 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables protein serine/threonine phosphatase activity. Involved in circadian regulation of gene expression; entrainment of circadian clock by photoperiod; and protein dephosphorylation. Acts upstream of or within blastocyst development; regulation of nucleocytoplasmic transport; and spermatogenesis. Located in mitochondrial outer membrane. Is expressed in several structures, including central nervous system and retina. Orthologous to human PPP1CC (protein phosphatase 1 catalytic subunit gamma). PHENOTYPE: Homozygotes for a targeted null mutation exhibit male infertility due to severely impaired spermiogenesis. [provided by MGI curators] |