Primary Identifier | MGI:1921346 | Organism | mouse, laboratory |
Chromosome | 5 | NCBI Gene Number | 74096 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables protein homodimerization activity and voltage-gated proton channel activity. Involved in several processes, including proton transmembrane transport; regulation of reactive oxygen species biosynthetic process; and response to zinc ion. Located in phagocytic vesicle membrane. Orthologous to human HVCN1 (hydrogen voltage gated channel 1). PHENOTYPE: Mice homozygous for a gene trap allele lack neutrophil and macrophage voltage-gated proton pumps. [provided by MGI curators] |