Primary Identifier | MGI:2444812 | Organism | mouse, laboratory |
Chromosome | 5 | NCBI Gene Number | 207565 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable calcium ion binding activity; calcium/calmodulin-dependent protein kinase activity; and calmodulin binding activity. Predicted to be involved in CAMKK-AMPK signaling cascade; positive regulation of protein phosphorylation; and protein autophosphorylation. Predicted to be located in cytosol. Is expressed in central nervous system; dorsal root ganglion; neural retina; testis; and trigeminal nerve. Orthologous to human CAMKK2 (calcium/calmodulin dependent protein kinase kinase 2). PHENOTYPE: Inactivation of this locus results in impaird long term potentiation and defects in some types of long term memory. [provided by MGI curators] |