Primary Identifier | MGI:1917900 | Organism | mouse, laboratory |
Chromosome | 5 | NCBI Gene Number | 70650 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable RNA binding activity. Predicted to be involved in mRNA 3'-end processing. Predicted to be located in nuclear body. Predicted to be part of TRAMP complex and catalytic step 2 spliceosome. Is expressed in several structures, including blastocyst; early embryo; eye; secondary oocyte; and trunk somite. Orthologous to human ZCCHC8 (zinc finger CCHC-type containing 8). PHENOTYPE: Mice homozygous for a null allele show partial lethality by E17.5 and lower survival rate in the first 3 months, small body size, infertility, small testes and ovaries, loss of sperm, fewer mature ovarian follicles, and oocyte maturation defects. [provided by MGI curators] |