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Protein Coding Gene : Hcar2 hydroxycarboxylic acid receptor 2

Primary Identifier  MGI:1933383 Organism  mouse, laboratory
Chromosome  5 NCBI Gene Number  80885
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Enables G protein-coupled receptor activity; GTP binding activity; and purinergic nucleotide receptor activity. Involved in G protein-coupled receptor signaling pathway. Is active in membrane. Is expressed in embryo. Orthologous to human HCAR2 (hydroxycarboxylic acid receptor 2) and HCAR3 (hydroxycarboxylic acid receptor 3).
PHENOTYPE: Mice homozygous for targeted mutations that inactivate the gene showed impaired reductions of free fatty acid (FFA) and triglyceride plasma levels in response to nicotinic acid. [provided by MGI curators]
  • synonyms:
  • Hcar2,
  • Niacr1,
  • hydroxycarboxylic acid receptor 2,
  • Pumag,
  • Gpr109b,
  • interferon-gamma inducible gene, Puma-g,
  • G protein-coupled receptor 109A,
  • PUMA-G,
  • niacin receptor 1,
  • HM74,
  • Gpr109a,
  • G protein-coupled receptor 109B

Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

2 Involved In Mutations

0 Strain

0 Transcripts

1 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

7 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

1 Driver For