Primary Identifier | MGI:1933383 | Organism | mouse, laboratory |
Chromosome | 5 | NCBI Gene Number | 80885 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables G protein-coupled receptor activity; GTP binding activity; and purinergic nucleotide receptor activity. Involved in G protein-coupled receptor signaling pathway. Is active in membrane. Is expressed in embryo. Orthologous to human HCAR2 (hydroxycarboxylic acid receptor 2) and HCAR3 (hydroxycarboxylic acid receptor 3). PHENOTYPE: Mice homozygous for targeted mutations that inactivate the gene showed impaired reductions of free fatty acid (FFA) and triglyceride plasma levels in response to nicotinic acid. [provided by MGI curators] |