| Primary Identifier | MGI:1915206 | Organism | mouse, laboratory |
| Chromosome | 5 | NCBI Gene Number | 67956 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable histone H4K20 methyltransferase activity and transcription corepressor activity. Predicted to be involved in negative regulation of nucleobase-containing compound metabolic process; peptidyl-lysine monomethylation; and regulation of DNA damage response, signal transduction by p53 class mediator. Predicted to be located in chromatin; cytosol; and nucleoplasm. Predicted to be active in nucleus and polytene chromosome. Is expressed in several structures, including extraembryonic component. Orthologous to human KMT5A (lysine methyltransferase 5A). PHENOTYPE: Mice homozygous for a gene trapped allele exhibit embryonic lethality. Mice homozygous for an allele lacking exon 7 die prior to implantation. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
