Primary Identifier | MGI:1920371 | Organism | mouse, laboratory |
Chromosome | 5 | NCBI Gene Number | 73121 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables filamin binding activity. Acts upstream of or within several processes, including actin filament bundle organization; negative regulation of bone mineralization involved in bone maturation; and negative regulation of chondrocyte development. Located in actin filament bundle. Is expressed in several structures, including alimentary system; respiratory system; sensory organ; skeleton; and unsegmented mesenchyme. Orthologous to human RFLNA (refilin A). PHENOTYPE: Mice homozygous for a null allele are viable and overtly normal, with no significant alterations in survival, body weight, body length, tibial length, or lumbar disk morphology. [provided by MGI curators] |