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Protein Coding Gene : Dtx2 deltex 2, E3 ubiquitin ligase
Primary Identifier  MGI:1921448 Organism  mouse, laboratory
Chromosome  5 NCBI Gene Number  74198
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to enable ubiquitin protein ligase activity. Acts upstream of or within Notch signaling pathway. Predicted to be located in nuclear membrane. Predicted to be active in nucleoplasm. Is expressed in several structures, including alimentary system; brain; gonad; nasal cavity epithelium; and pharyngo-tympanic tube. Orthologous to human DTX2 (deltex E3 ubiquitin ligase 2).
PHENOTYPE: Mice homozygous for a knock-out allele are viable and overtly normal with no detectable abnormalities in T or B cell development. [provided by MGI curators]
  • synonyms:
  • deltex 2, E3 ubiquitin ligase,
  • expressed sequence AA408415,
  • AU022494,
  • Dtx2,
  • 2610524D08Rik,
  • MGI:2140736,
  • RIKEN cDNA 2610524D08 gene,
  • expressed sequence AU022494,
  • MGI:2141064,
  • AA408415
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