| Primary Identifier | MGI:1917353 | Organism | mouse, laboratory |
| Chromosome | 5 | NCBI Gene Number | 70103 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables chromatin binding activity and histone deacetylase binding activity. Involved in several processes, including hematopoietic stem cell homeostasis; intestinal stem cell homeostasis; and positive regulation of macromolecule biosynthetic process. Acts upstream of or within negative regulation of G0 to G1 transition; negative regulation of transcription by RNA polymerase II; and regulation of T cell proliferation. Located in nucleus. Is expressed in early conceptus; heart; and lens. Orthologous to human ZNHIT1 (zinc finger HIT-type containing 1). PHENOTYPE: Mice homozygous for a knock-out allele show embryonic lethality during peri-implantation stages with abnormal inner cell mass, primitive endoderm, and trophectoderm morphology. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
