Primary Identifier | MGI:1933527 | Organism | mouse, laboratory |
Chromosome | 5 | NCBI Gene Number | 83701 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables DNA binding activity. Involved in neuronal stem cell population maintenance; positive regulation of neurogenesis; and regulation of gene expression. Located in cytoplasm and nucleoplasm. Is expressed in several structures, including genitourinary system; liver; lung; retina; and spleen. Orthologous to human SRRT (serrate, RNA effector molecule). PHENOTYPE: Mice homozygous for a null allele display embryonic lethality before somite formation, increased apoptosis, and when cultured most fail to hatch from the zona pellucida. [provided by MGI curators] |