Primary Identifier | MGI:1343458 | Organism | mouse, laboratory |
Chromosome | 5 | NCBI Gene Number | 22051 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable interleukin-1 receptor binding activity and kinase binding activity. Involved in chordate embryonic development. Predicted to be located in several cellular components, including cytoskeleton; cytosol; and nucleus. Predicted to be active in cytoplasm; focal adhesion; and stress fiber. Is expressed in several structures, including alimentary system; central nervous system; early conceptus; genitourinary system; and skin. Orthologous to human TRIP6 (thyroid hormone receptor interactor 6). PHENOTYPE: Mice homozygous for a null allele exhibit poorly differentiated brain ependymal and choroid plexus epithelial cells with fewer and shorter cilia and develop hydrocephalus. [provided by MGI curators] |