Primary Identifier | MGI:1888677 | Organism | mouse, laboratory |
Chromosome | 5 | NCBI Gene Number | 57330 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Acts upstream of or within insulin-like growth factor receptor signaling pathway. Predicted to be part of protein-containing complex. Predicted to be active in cytosol. Is expressed in several structures, including genitourinary system; liver; lung; nervous system; and spleen. Orthologous to human GIGYF1 (GRB10 interacting GYF protein 1). PHENOTYPE: Homozygous null mice die shortly after birth. Heterozygotes exhibit excessive grooming, decreased locomotor activity, impaired social memory, and increased CA2 glutamatergic neurons. [provided by MGI curators] |