Primary Identifier | MGI:1194882 | Organism | mouse, laboratory |
Chromosome | 5 | NCBI Gene Number | 16369 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables phosphatidylinositol 3-kinase activator activity and phosphatidylinositol 3-kinase binding activity. Involved in positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction. Located in plasma membrane. Is expressed in several structures, including heart; liver; lung; metanephros; and spleen. Orthologous to human IRS3P (insulin receptor substrate 3, pseudogene). PHENOTYPE: Mice homozygous for a targeted mutation are viable, fertile and display no detectable abnormalities in growth or glucose homeostasis. [provided by MGI curators] |