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Protein Coding Gene : Mepce methylphosphate capping enzyme

Primary Identifier  MGI:106477 Organism  mouse, laboratory
Chromosome  5 NCBI Gene Number  231803
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to enable 7SK snRNA binding activity and RNA 5'-gamma-phosphate methyltransferase activity. Acts upstream of or within negative regulation of transcription by RNA polymerase II and positive regulation of G1/S transition of mitotic cell cycle. Predicted to be located in nucleus. Predicted to be part of 7SK snRNP. Is expressed in several structures, including adrenal gland; alimentary system; brain; early conceptus; and genitourinary system. Orthologous to human MEPCE (methylphosphate capping enzyme).
PHENOTYPE: Mice homozygous for a knock-out allele show complete embryonic lethality prior to organogenesis. [provided by MGI curators]
  • synonyms:
  • Mepce,
  • bin3, bicoid-interacting 3, homolog (Drosophila),
  • methylphosphate capping enzyme,
  • MGC:28888,
  • D5Wsu46e,
  • MGD-MRK-34171,
  • DNA segment, Chr 5, Wayne State University 46, expressed,
  • MGC:30590,
  • Bcdin3

Features --> Cross References

Genome

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Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

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Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

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