Primary Identifier | MGI:88610 | Organism | mouse, laboratory |
Chromosome | 5 | NCBI Gene Number | 13113 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable several functions, including caffeine oxidase activity; iron ion binding activity; and monooxygenase activity. Acts upstream of or within positive regulation of gene expression. Predicted to be located in cytoplasm. Is expressed in several structures, including heart; liver; lung; metanephros; and spleen. Human ortholog(s) of this gene implicated in B-lymphoblastic leukemia/lymphoma; acute lymphoblastic leukemia; chronic myeloid leukemia; essential hypertension; and familial Mediterranean fever. Orthologous to several human genes including CYP3A7 (cytochrome P450 family 3 subfamily A member 7). PHENOTYPE: Mice homozygous for a knock-out allele show no apparent alterations in hematology, plasma clinical chemistry or pathology. [provided by MGI curators] |