Primary Identifier | MGI:103163 | Organism | mouse, laboratory |
Chromosome | 5 | NCBI Gene Number | 12007 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to be involved in several processes, including antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent; detection of chemical stimulus involved in sensory perception of bitter taste; and positive regulation of T cell mediated cytotoxicity. Predicted to be active in external side of plasma membrane and extracellular space. Is expressed in several structures, including brain; exocrine gland; genitourinary system; gut; and liver and biliary system. Human ortholog(s) of this gene implicated in prostate carcinoma. Orthologous to human AZGP1 (alpha-2-glycoprotein 1, zinc-binding). PHENOTYPE: Mice homozygous for a knock-out allele exhibit impaired lipolysis and increased body weight when fed standard food or a high fat diet. [provided by MGI curators] |