| Primary Identifier | MGI:1924303 | Organism | mouse, laboratory |
| Chromosome | 5 | NCBI Gene Number | 77053 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables lamin binding activity. Involved in centrosome localization; meiotic attachment of telomere to nuclear envelope; and nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration. Acts upstream of or within homologous chromosome pairing at meiosis. Located in chromosome, telomeric region; cytoplasm; and nuclear inner membrane. Is expressed in epidermis; intercostal muscle; spermatocyte; and spermatozoon. Orthologous to human SUN1 (Sad1 and UNC84 domain containing 1). PHENOTYPE: Mice homozygous for a null allele exhibit sterility due to arrested meiosis, hearing loss associated with outer hair cell degeneration, abnormal cerebellum development, ataxia, impaired motor coordination, and abnormal Purkinje cell migration. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
