| Primary Identifier | MGI:2442201 | Organism | mouse, laboratory |
| Chromosome | 5 | NCBI Gene Number | 231821 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable GTPase activator activity; inositol 1,3,4,5 tetrakisphosphate binding activity; and phosphatidylinositol-3,4,5-trisphosphate binding activity. Predicted to be located in cytosol and nucleus. Predicted to be active in cytoplasm; intracellular membrane-bounded organelle; and plasma membrane. Is expressed in nervous system. Orthologous to human ADAP1 (ArfGAP with dual PH domains 1). PHENOTYPE: Mice homozygous for a knock-out allele exhibit increased dendritic spine density and spine structural plasticity in hippocampal neurons, enhanced long term potentiation, and improved hippocampus-dependent spatial memory in a location recognition task. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
