Primary Identifier | MGI:2442479 | Organism | mouse, laboratory |
Chromosome | 5 | NCBI Gene Number | 243312 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable protein phosphatase inhibitor activity. Involved in synaptic membrane adhesion. Acts upstream of or within several processes, including chemical synaptic transmission; synapse assembly; and visual perception. Located in dendrite and excitatory synapse. Is active in axon terminus; glutamatergic synapse; and postsynaptic density membrane. Is expressed in several structures, including adrenal gland; eye; gut; nervous system; and reproductive system. Orthologous to human ELFN1 (extracellular leucine rich repeat and fibronectin type III domain containing 1). PHENOTYPE: Homozygous mutants display impaired coordination, hyperactivity, lower anxiety-related response, and increased susceptibility to induced seizures. [provided by MGI curators] |