Primary Identifier | MGI:109280 | Organism | mouse, laboratory |
Chromosome | 5 | NCBI Gene Number | 17766 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity and snoRNA binding activity. Predicted to be involved in DNA protection and purine nucleoside catabolic process. Predicted to be located in several cellular components, including acrosomal vesicle; mitochondrial matrix; and nuclear membrane. Predicted to be active in cytoplasm. Orthologous to human NUDT1 (nudix hydrolase 1). PHENOTYPE: Aging mice homozygous for a knock-out allele show increased incidence of tumor formation in the lung, liver and stomach. [provided by MGI curators] |