Primary Identifier | MGI:2443816 | Organism | mouse, laboratory |
Chromosome | 5 | NCBI Gene Number | 231834 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable identical protein binding activity and phosphatidylinositol binding activity. Predicted to be involved in early endosome to Golgi transport and intracellular protein transport. Predicted to be located in intracellular membrane-bounded organelle. Predicted to be part of retromer complex. Predicted to be active in early endosome membrane. Is expressed in cerebral cortex ventricular layer and small intestine. Orthologous to human SNX8 (sorting nexin 8). PHENOTYPE: Mice homozygous for a knock-out allele exhibit increased susceptibility to lethal infection by Listeria monocytogenes. [provided by MGI curators] |